Semaglutide (GLP-1)
Semaglutide is a GLP-1 receptor agonist that mimics the action of the hormone glucagon-like peptide-1, which plays a key role in regulating appetite and insulin secretion. By enhancing insulin sensitivity and suppressing appetite, semaglutide helps individuals achieve significant weight loss and better glycemic control in those with type 2 diabetes. Additionally, it slows gastric emptying, leading to prolonged feelings of fullness after meals, further supporting weight management efforts.
Trizepatide (GIP/GLP-1)
Tirzepatide is a dual GIP and GLP-1 receptor agonist that enhances glucose control and promotes weight loss by targeting multiple pathways in the body. It stimulates insulin secretion in response to meals while also reducing appetite and slowing gastric emptying, leading to greater satiety and reduced caloric intake. This multifaceted approach not only improves glycemic control for individuals with type 2 diabetes but also supports significant weight loss, making it a promising treatment option.
Dosing
The best dosing approach for GLP-1 receptor agonists for weight loss typically starts with a low dose to minimize side effects and allow the body to adjust. Gradual titration is often recommended, where the dose is increased incrementally based on tolerance and response, until the optimal therapeutic dose is reached. This tailored approach helps enhance weight loss efficacy while minimizing gastrointestinal side effects, ultimately leading to better adherence and sustained results.
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